OFLOXACINA OFTALDAY / Eye drops 5ml

OFLOXACIN OFTALDAY

ADMINISTRATION: Ocular

Description

Sterile eye drops containing 0.3% ofloxacin and hydroxypropylmethylcellulose (HPMC).

Presentation

5 mL dropper bottle with an atraumatic applicator.

Action

Ofloxacin is a latest-generation fluoroquinolone antibiotic with excellent penetration into the corneal structure due to its lipophilic properties. Its optimal solubility at a neutral pH minimizes precipitation of the active ingredient, ensuring a higher concentration in tears.

• Greater corneal penetration than ciprofloxacin and higher potency than norfloxacin.

• Inhibits topoisomerase IV and bacterial DNA gyrase, preventing DNA replication and transcription.

• Effective against a broad spectrum of bacteria, including Gram-positive, Gram-negative, anaerobes, mycoplasma, and Chlamydia.

Indications

Used for the treatment of bacterial conjunctivitis, corneal ulcers, secondary infections due to keratoconjunctivitis sicca, and as a pre- and post-surgical ophthalmic antibiotic in cats and dogs.

Formula

Each 100 mL of solution contains:

• Ofloxacin – 0.3 g

• Excipients – q.s.

Dosage and Administration

• Dogs and cats: Instill 1 drop into the conjunctival sac every 12 hours for 7 days, or as directed by the veterinarian.

• In severe cases, administer every 4 to 6 hours for the first 48 hours.

Contraindications

• Hypersensitivity to ofloxacin, other quinolones, or any excipients.

Side Effects

• Mild local irritation may occur in some cases, but it does not lead to complications.

Usage Restrictions

• Not specified.

Precautions

• Avoid contact of the dropper tip with the eye or any surface.

• Tightly close the bottle after each use.